Increase in Cerebral Blood Flow indicated by increased Cerebral Arterial area and pixel intensity on brain magnetic resonance angiogram following correction of Cervical Lordosis.
PUBLISHED: Brain Circ. 2019 Jan-Mar;5(1):19-26. doi: 10.4103/bc.bc_25_18. Epub 2019 Mar 27. Pub Med: https://www.ncbi.nlm.nih.gov/pubmed/31001596
AUTHORS: Katz EA1, Katz SB1, Fedorchuk CA2, Lightstone DF2, Banach CJ1, Podoll JD3.
- Private Practice, Boulder, CO, USA.
- Private Practice, Cumming, GA, USA.
- Molecular, Cellular and Developmental Biology Department, University of Colorado Boulder, Boulder, CO, USA.
CONTEXT: Loss of cervical lordosis is associated with decreased vertebral artery hemodynamics.
AIM: The aim of this study is to evaluate cerebral blood flow changes on brain magnetic resonance angiogram (MRA) in patients with loss of cervical lordosis before and following correction of cervical lordosis.
SETTINGS AND DESIGN: This study is a retrospective consecutive case series of patients in a private practice.
MATERIALS AND METHODS: Cervical lordosis of seven patients (five females and two males, 28-58 years) was measured on lateral cervical radiographs ranging from -13.1° to 19.0° (ideal is -42.0°). Brain MRAs were analyzed for pixel intensities representing blood flow. Pixel intensity of the cerebral vasculature was quantified, and percentage change was determined.
STATISTICAL ANALYSIS USED: A Student’s t-test established significance of the percentage change in cerebral blood flow between pre- and postcervical lordosis adjustment images. Regression analysis was performed. An a priori analysis determined correlation between cervical lordosis and change in MRA pixel intensity. The statistician was blinded to the cervical lordosis.
RESULTS: Pixel intensity increased 23.0%-225.9%, and a Student’s t-test determined that the increase was significant (P < 0.001). Regression analysis of the change in pixel intensity versus the cervical lordosis showed that as the deviation from a normal cervical lordosis increases, percentage change in pixel intensity on MRA decreases.
CONCLUSION: These results indicate that correction of cervical lordosis may be associated with an immediate increase in cerebral blood flow.
Further studies are needed to confirm these findings and understand clinical implications.
The Spinal Centre – Neuro-Musculoskeletal SolutionsThe Spinal Centre provides the Best Natural Medicines, Health Products and Nutritional Solutions to Free You of Pain and Improve Your Spinal Health.The Spinal Centre is a leader in the management and treatment of spinal pain and disability including:
- Chronic Back and Neck Pain
- Cervical and Lumbar Disc Injuries with or without neruological changes
- All forms of arthritis including rheumatoid arthritis, psoriatic arthritis and osteoarthritis
- Neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease
- Neuromuscular problems such as chronic back pain, headaches, migraines, neck or spinal pains
- Myofascial pain syndromes such as fibromyalgia, diffuse muscular or joint pains
- Austistic spectrum disorders including ADD, ADHD, learning difficulties and autism
- Fatigue, energy and mood disorders including chronic fatigue and depression
The Spinal Centre focuses on resolution with the development of individualised treatment programs using Conservative and Integrative Medicine; combining genetic, metabolic and nutritional testing with specific natural medicines to enhance your health and achieve your genetic potential.We have helped thousands – Why Not You?